FREQUENCY OF REMISSION AFTER TREATMENT WITH HYPER CVAD PROTOCOL IN NEWLY DIAGNOSED PATIENTS OF ACUTE LYMPHOBLASTIC LEUKEMIA PRESENTING TO JINNAH HOSPITAL LAHORE

  • Muhammad Kashif Postgraduate Resident, Medical Oncology, AIMC/Jinnah Hospital, Lahore.
  • Tahir Mehmood Consultant Medical Oncologist, FMU/Allied Hospital, Faisalabad.
  • Kausar Bano et al. Assistant Professor, Medical Oncology, AIMC/Jinnah Hospital, Lahore
Keywords: Acute Lymphoblastic Leukemia, Complete and Partial Remission, Hyper CVAD

Abstract

ABSTRACT:

OBJECTIVE: The objective of this study was to determine the frequency of complete and partial remission after 2 courses of hyper CVAD regimen in newly diagnosed patients of acute lymphoblastic leukemia (ALL).
MATERIAL AND METHODS: This study was conducted on 100 patients of ALL presenting to the oncology department of Jinnah Hospital, Lahore and fulfilling the inclusion criteria from 01-012016 to 30-12-2016. Patients were undergone treatment with hyper CVAD regimen according to the standard protocol. Complete or partial remission rate was checked after 2 session of hyper CVAD regimen. CT scan (chest and abdomen) was performed for confirmation of extramedullary disease.

RESULTS: The mean age of study population was 35.68 ± 8.69 years. There were 48% male patients while female patients were 52%. Complete remission was present in 72% patients. Partial remission was present in 24% patients. There was no significant association between complete remission and age (p-value=0.497). No significant association was found between partial remission and age (p-value=0.103). Significant association was found between partial remission and complete remission with gender having p-value=0.001 and 0.01 respectively.

CONCLUSION: The frequency of complete and partial remission after 2 courses of hyper CVAD regimen in newly diagnosed patients of ALL was 72% and 24% respectively. Effect modifiers have no significant influence except gender.

Published
2019-12-06
How to Cite
Muhammad Kashif, Tahir Mehmood, & Kausar Bano et al. (2019). FREQUENCY OF REMISSION AFTER TREATMENT WITH HYPER CVAD PROTOCOL IN NEWLY DIAGNOSED PATIENTS OF ACUTE LYMPHOBLASTIC LEUKEMIA PRESENTING TO JINNAH HOSPITAL LAHORE. Journal of University Medical & Dental College, 10(4), 16-20. https://doi.org/10.37723/jumdc.v10i4.72
Section
Original Articles