Coronary Artery disease prevalence in patients having essential hypertension with Or without diabetes Mellitus detected by Cardiac MIBI scan

Effect of hypertension and diabetes Mellites on Coronary Artery Disease

Abstract

BACKGROUND & OBJECTIVE: The aim of this retrospective study was to find the prevalence of coronary artery disease (CAD) in hypertensive patients with or without diabetes mellitus.

METHODOLOGY: Data of patients having essential hypertension (n=931) referred to PINUM from April 2017 to December 2018 for stress/rest cardiac MIBI scan was analyzed. This data was divided into two groups. HD group contains data of patients having hypertension with diabetes mellitus (n=456, 48.98% of total population, M:F=245:211). While data of patients having hypertension without diabetes mellitus was placed in H group (n=475, 51.02% of total population, M: F=254:221).

RESULTS: Prevalence of CAD is higher in HD group than in H group (47.8% vs. 30.1%; p<0.001). CAD is more prevalent in males than females in both groups (53.9 % vs. 40.8% in HD group, and 39.4% vs. 19.5% in H group). This difference in prevalence of CAD in HD and H groups is more marked in females (40.8% vs. 19.5%; p<0.001) than males (53.9 % vs. 39.4%; p=0.001). Prevalence of CAD in patients with typical presentation is not statistically significant in HD and H groups (72.3% vs. 68.4%; p=0.645), while in subjects with atypical presentation prevalence is significantly higher in HD group than H group (40.8% vs. 26.8%; p<0.001).

CONCLUSION: Prevalence of CAD is higher in the group of patients having essential hypertension with diabetes mellitus than the group of patients having essential hypertension without diabetes mellitus.